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Ching-Hon Pui Selected Research

rasburicase (Elitek)

1/2019Concordance between glucose-6-phosphate dehydrogenase (G6PD) genotype and phenotype and rasburicase use in patients with hematologic malignancies.
6/2008Guidelines for the management of pediatric and adult tumor lysis syndrome: an evidence-based review.
1/2005Recombinant urate oxidase (rasburicase) in the prophylaxis and treatment of tumor lysis syndrome.
3/2003Recombinant urate oxidase for prevention of hyperuricemia and tumor lysis syndrome in lymphoid malignancies.
4/2002Rasburicase: a potent uricolytic agent.

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Ching-Hon Pui Research Topics

Disease

199Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
11/2022 - 01/2002
79Leukemia
07/2022 - 04/2002
67Neoplasms (Cancer)
01/2022 - 04/2002
36Residual Neoplasm
01/2022 - 06/2002
25Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
10/2022 - 10/2002
18Infections
10/2022 - 09/2003
16Osteonecrosis (Kienbock's Disease)
01/2021 - 10/2004
13Hypersensitivity (Allergy)
07/2022 - 09/2005
11Philadelphia Chromosome
01/2021 - 01/2009
8Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
01/2022 - 02/2009
7Pain (Aches)
01/2022 - 03/2008
7Hematologic Neoplasms (Hematological Malignancy)
01/2021 - 04/2010
7Leukoencephalopathies
10/2016 - 12/2004
6Overweight
01/2021 - 12/2006
6Thrombosis (Thrombus)
01/2020 - 08/2003
6Febrile Neutropenia
01/2020 - 04/2008
6Genetic Predisposition to Disease (Genetic Predisposition)
11/2019 - 01/2006
6Second Primary Neoplasms (Neoplasms, Second)
10/2019 - 07/2002
5Obesity
01/2021 - 12/2002
5Peripheral Nervous System Diseases (PNS Diseases)
01/2021 - 02/2015
4Neuralgia (Stump Neuralgia)
01/2022 - 12/2011
4Brain Neoplasms (Brain Tumor)
01/2021 - 02/2005
4Hypothyroidism
12/2019 - 04/2006
4Seizures (Absence Seizure)
12/2019 - 08/2003
4Hodgkin Disease (Hodgkin's Disease)
01/2018 - 03/2006
4Neutropenia
03/2011 - 01/2004
3Pancreatitis
01/2021 - 12/2009
3Chronic Disease (Chronic Diseases)
10/2019 - 07/2009
3Hypogonadism (Hypergonadotropic Hypogonadism)
06/2019 - 07/2007
3Sepsis (Septicemia)
01/2019 - 09/2003
3Glucosephosphate Dehydrogenase Deficiency
01/2019 - 04/2002
3Central Nervous System Diseases (CNS Diseases)
11/2018 - 01/2006
3Hyperglycemia
01/2017 - 12/2002
3Myelodysplastic Syndromes (Myelodysplastic Syndrome)
12/2016 - 11/2002
3Acute Kidney Injury (Acute Renal Failure)
12/2016 - 09/2012
3Hyperuricemia
01/2010 - 03/2003

Drug/Important Bio-Agent (IBA)

38Methotrexate (Mexate)FDA LinkGeneric
01/2021 - 07/2002
26Asparaginase (Elspar)FDA Link
01/2022 - 12/2002
20Pharmaceutical PreparationsIBA
01/2022 - 06/2002
17Dexamethasone (Maxidex)FDA LinkGeneric
01/2021 - 11/2004
16GlucocorticoidsIBA
01/2021 - 12/2002
15Biological ProductsIBA
10/2020 - 08/2007
13Vincristine (Oncovin)FDA LinkGeneric
01/2021 - 02/2002
12Mercaptopurine (6 Mercaptopurine)FDA LinkGeneric
01/2022 - 01/2002
10DNA (Deoxyribonucleic Acid)IBA
01/2022 - 01/2004
10Tyrosine Kinase InhibitorsIBA
01/2022 - 01/2009
9Cytarabine (Cytosar-U)FDA LinkGeneric
12/2019 - 10/2002
8Etoposide (VP 16)FDA LinkGeneric
01/2021 - 04/2002
7AntibodiesIBA
07/2022 - 01/2011
7Growth Hormone (Somatotropin)IBA
01/2021 - 07/2002
7NucleotidesIBA
01/2021 - 06/2003
6pegaspargase (Oncaspar)FDA Link
07/2022 - 10/2019
6Messenger RNA (mRNA)IBA
07/2022 - 08/2006
6Proteins (Proteins, Gene)FDA Link
06/2021 - 01/2005
6EnzymesIBA
01/2021 - 03/2003
6Thioguanine (Tioguanine)FDA Link
01/2021 - 06/2003
6Indicators and Reagents (Reagents)IBA
04/2015 - 06/2002
5ChromatinIBA
01/2022 - 11/2019
5RNA (Ribonucleic Acid)IBA
01/2022 - 04/2015
5Dasatinib (BMS 354825)FDA Link
01/2022 - 01/2020
5Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2021 - 01/2012
5Clofarabine (Clolar)FDA Link
01/2021 - 08/2011
5Anti-Bacterial Agents (Antibiotics)IBA
01/2021 - 09/2003
52-mercaptopurineIBA
01/2020 - 01/2002
5AntimetabolitesIBA
01/2020 - 11/2004
5Prednisone (Sone)FDA LinkGeneric
01/2019 - 01/2004
5rasburicase (Elitek)FDA Link
01/2019 - 04/2002
4Opioid Analgesics (Opioids)IBA
01/2022 - 12/2011
4AntigensIBA
01/2021 - 06/2011
4Folic Acid (Vitamin M)FDA LinkGeneric
12/2020 - 10/2004
4Biomarkers (Surrogate Marker)IBA
01/2020 - 01/2006
4SteroidsIBA
01/2016 - 12/2002
4gamma-Glutamyl Hydrolase (Carboxypeptidase G2)IBA
05/2014 - 07/2002
3Gabapentin (Neurontin)FDA LinkGeneric
01/2022 - 12/2011
3Sorafenib (BAY 43-9006)FDA Link
01/2022 - 08/2011
3Transcription Factors (Transcription Factor)IBA
11/2021 - 09/2014
3venetoclaxIBA
01/2021 - 01/2020
3Prednisolone (Predate)FDA LinkGeneric
01/2020 - 08/2004
3Alkylating AgentsIBA
12/2019 - 10/2014
3Daunorubicin (Cerubidine)FDA LinkGeneric
10/2019 - 08/2004
3Phosphotransferases (Kinase)IBA
01/2018 - 08/2012
3purineIBA
01/2016 - 09/2004
3Dihydrotachysterol (AT 10)IBA
12/2013 - 07/2007
3Urate Oxidase (Uricase)IBA
01/2010 - 03/2003
3CladribineFDA LinkGeneric
01/2010 - 10/2002

Therapy/Procedure

134Therapeutics
10/2022 - 02/2002
71Drug Therapy (Chemotherapy)
01/2022 - 07/2002
26Remission Induction
01/2022 - 07/2002
18Radiotherapy
01/2020 - 08/2003
13Cranial Irradiation
01/2021 - 01/2004
10Aftercare (After-Treatment)
10/2022 - 08/2004
9Hematopoietic Stem Cell Transplantation
01/2018 - 10/2003
6Cell Transplantation
01/2019 - 02/2006
4Induction Chemotherapy
01/2021 - 03/2011
4Anesthesia
01/2020 - 11/2007
4Transplantation
07/2013 - 02/2010
3Central Venous Catheters
09/2022 - 07/2009
3Antibiotic Prophylaxis
01/2021 - 07/2008
3Immunotherapy
01/2020 - 01/2019
3Combination Drug Therapy (Combination Chemotherapy)
07/2013 - 04/2005